首页|Box-Behnken响应面法优选樟帮酒润麸炒桑枝最佳炮制工艺

Box-Behnken响应面法优选樟帮酒润麸炒桑枝最佳炮制工艺

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目的 优选樟帮酒润麸炒桑枝最佳炮制工艺.方法 以桑皮苷A、绿原酸、白藜芦醇、白藜芦醇苷、氧化白藜芦醇、桑色素、桑酮G、桑辛素8个成分总含量为考查指标,对樟帮酒润麸炒桑枝中麦麸用量、黄酒用量、炒制温度、浸润时间、炮制时间5个影响因素进行单因素考察,运用Box-Behnken响应面法进行试验设计,优选酒润麸炒桑枝最佳炮制工艺.结果 响应面法优选樟帮酒润麸炒桑枝最佳炮制工艺为浸润时间116 min,麦麸用量19%,黄酒用量10%,炒制时间7 min,炒制温度237 ℃,该工艺条件下,桑枝饮片中8个成分平均总含量为787.8 μg/g,RSD值为0.98%.结论 优选的樟帮酒润麸炒桑枝最佳炮制工艺稳定可靠、重复性好,可更好保障樟帮酒润麸炒桑枝质量.
Optimal processing technology of Zhangbang wine moistening bran stir-fried Mori Ramulus through Box-Behnken response surface method
Objective To optimize the technology of Zhangbang wine moistening bran stir-fried Mori Ramulus.Methods Using the total contents of 8 components including mulberry bark glycoside A,chlorogenic acid,resveratrol,resveratrol glycoside,oxidized resveratrol,mulberry pigment,mulberry ketone G,and mulberry saponin as the examination indicators,single factor investigation of five influencing factors of Zhangbang wine moistening bran stir-fried Mori Ramulus:wheat bran dosage,yellow wine dosage,frying temperature,soaking time,and processing time was conducted.Box Behnken response surface methodology was used for experimental design,to optimize processing technology for Zhangbang wine moistening bran stir-fried Mori Ramulus.Results The optimal processing technology of the response surface method was:soaking time 116 min,wheat bran amount 19%,rice wine amount 10%,roasting time 7 min,and roasting temperature 237 ℃.Under these conditions,the average total content of eight components in the prepared Mori Ramulus decoction pieces was 787.8 μg/g,and RSD was 0.98%.Conclusion The optimal processing technology of Zhangbang wine moistening bran stir-fried Mori Ramulus is stable,reliable and repeatable,which can better guarantee the quality of Zhangbang wine moistening bran stir-fried Mori Ramulus.

Mori RamulusBox-Behnken response surface methodZhangbangWine moistening bran stir-fryProcessing(TCD)

刘雅琪、周彦如、谢作桦、周立翔、盛文胜

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江西德上医药研究院有限公司,樟树 331200

江西中医药大学药学院,南昌 330004

桑枝 Box-Behnken响应面法 樟帮 酒润麸炒 炮制(中药)

江西省中医药管理局科技计划课题

2020Z010

2024

国际中医中药杂志
中华医学会,中国中医科学院中医药信息研究所

国际中医中药杂志

CSTPCD
影响因子:0.411
ISSN:1673-4246
年,卷(期):2024.46(8)
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