首页|托疮生肌法治疗难愈性创面机制研究进展

托疮生肌法治疗难愈性创面机制研究进展

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托疮生肌法属中医外科疮疡内治法"补托法",其义为扶正托毒、祛腐生肌,代表方包括托里消毒散、黄芪汤、排脓内托散、神功内托散等,多以黄芪、人参、白术、当归等补益类药物佐以皂角刺、金银花等祛邪类药物以扶正托毒.托疮生肌法治疗难愈性创面主要机制包括止血阶段抗凝血、炎症阶段抗炎与抑菌、增殖阶段促进血管生成,以及重塑阶段促进肉芽组织生长与再上皮化.现有研究对于托疮生肌法的理解多为补气托疮法,其他治法相关文献较少.今后研究应重视中医的整体性和系统性,加强对托疮生肌法复方的多组分分析及信号通路上下游的连续性研究,提高研究质量.
Research progress in mechanism of Tuochuang Shengji therapy in treating refractory wounds
Tuochuang Shengji therapy(the therapy of supporting sores and generating muscle)belongs to the"tonic method"of internal treatment of TCM surgical sores and ulcers.Its meaning is to strengthen the healthy qi and discharge purulent,remove the rot and promote the growth of the muscle.The representative prescriptions include Tuoli Xiaodu Powder,Huangqi Decoction,Painong Neituo Powder,Shengong Neituo Powder,etc.,mostly with Astragali Radix,Ginseng Radix et Rhizoma,Atractylodis Macrocephalae Rhizoma,Angelicae Sinensis Radix and other tonic drugs,supplemented by Gleditsiae Spina,Lonicerae Japonicae Flos and other anti-pathogenic factor drugs to strengthen the the healthy qi and discharge purulent.The main mechanism of Tuochuang Shengji method in the treatment of refractory wounds include anticoagulation in the hemostasis stage,anti-inflammation and bacteriostasis in the inflammation stage,promoting angiogenesis in the proliferation stage,and promoting granulation tissue growth and re-epithelialization in the remodeling stage.The existing research on the understanding of Tuochuang Shengji therapy is mostly the method of tonifying qi and supporting sores,and there is few related literature on the remaining treatment methods.In the future,the integrity and systematicness of TCM should be paid attention to,the multi-component analysis of Tuochuang Shengji compound and the continuous research on the upstream and downstream of signaling pathways should be strengthened,the quality of research should be improved.

Soreand ulcerRefractory woundsTuochuang Shengji therapySurgery(TCM)MechanismReview

杜昊洋、付海琪、梁勇、高原

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内蒙古医科大学,呼和浩特 010000

内蒙古自治区中医医院肛肠一科,呼和浩特 010000

疮疡 难愈性创面 托疮生肌法 中医外科学 作用机制 综述

第十二批"草原英才"工程高层次培养人才项目(2022年)内蒙古自治区中医药中青年领军人才培育项目内蒙古医科大学联合项目Inner Mongolia Autonomous Region Traditional Chinese Medicine Middle and Young Leading Talents Cultivation Project

内卫中蒙传承字[2022]88号YKD2021LH051[2022]88

2024

10.3760/cma.j.cn115398-20231008-00037

国际中医中药杂志
中华医学会,中国中医科学院中医药信息研究所

国际中医中药杂志

CSTPCD
影响因子：0.411
ISSN：1673-4246
年,卷(期)：2024.46(8)
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