世界临床药物2024,Vol.45Issue(2) :107-111.DOI:10.13683/j.wph.2024.02.001

性激素在绝经激素治疗中的应用及展望

Application and prospects of sex hormones in menopausal hormone therapy

马菱蔚 冯源原 孙鑫萌 吴志勇 张炜 夏和霞
世界临床药物2024,Vol.45Issue(2) :107-111.DOI:10.13683/j.wph.2024.02.001

性激素在绝经激素治疗中的应用及展望

Application and prospects of sex hormones in menopausal hormone therapy

马菱蔚 1冯源原 2孙鑫萌 1吴志勇 1张炜 2夏和霞2
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作者信息

  • 1. 复旦大学附属妇产科医院妇科,上海 200011
  • 2. 复旦大学附属妇产科医院妇科,上海 200011;上海市女性生殖内分泌相关疾病重点实验室,上海 200011
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摘要

随着女性卵巢功能的衰退,全身其他重要器官功能也逐步下降,部分围绝经期女性出现躯体、精神症状或疾病,影响女性生活质量.绝经激素治疗(menopause hormone therapy,MHT)通过添加外源性性激素,改善并缓解卵巢功能下降甚至衰竭所导致的相关症状.该文就孕激素、雌激素以及雌孕激素复方制剂等各类性激素在MHT中的应用范围、常用方案及风险获益进行探讨、总结,以期对围绝经期女性用药提供参考.

Abstract

With the failure of ovarian function,the function of other important organs is also gradually decreased.Some perimenopausal women experience physical,mental symptoms or illnesses,which affect their quality of life.Menopausal hormone therapy(MHT)improves and alleviates the symptoms caused by decline or even failure of ovarian function by adding exogenous sex hormones.This paper reviewed the application scope,commonly regimens and the risks and benefits of various sex hormones,including progestogens,estrogens,combined estrogen-progestogens preparations in MHT,in order to provide a reference for drug use in perimenopausal women.

关键词

绝经激素治疗/雌激素/孕激素/女性健康

Key words

menopausal hormone therapy/estrogen/progesterone/women's health

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出版年

2024
世界临床药物
上海医药工业研究院

世界临床药物

CSTPCD
影响因子:0.849
ISSN:1672-9188
参考文献量25
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