Research progress of cuprotosis and anticancer mechanism of copper carrier drugs
Copper is involved in many life processes,and imbalance of copper homeostasis leads to cell death,a process known as copper death.Tumor cells maintained higher cellular activity and higher copper load.Copper carriers and related drugs can induce copper overload in tumor cells and lead to copper death of tumor cells.This article reviewed the relationship between copper death and cancer and the anticancer mechanism of copper carrier drugs.