Clinical progress of pulmonary surfactant in the treatment of neonatal respiratory distress syndrome
Neonatal respiratory distress syndrome(NRDS)is a neonatal respiratory disease caused by insufficient secretion of pulmonary surfactant(PS)due to immature lung tissue,it can cause progressive dyspnea,respiratory failure and other lung symptoms.PS replacement therapy is widely used in clinical practice to treat NRDS.With the deepening of related studies and the continuous enrichment of clinical medication knowledge,more and more clinical optimal drug delivery routes of PS have been reported.This article reviewed the clinical application of PS in NRDS and summarized the latest research results of new PS,administration route,administration timing,administration dose,and administration device,and also discussed the possibility application of PS in other respiratory diseases,to provide the reference for improving the level of clinical application of PS.
neonatal respiratory distress syndromepulmonary surfactantpediatric drugnon-invasive drug delivery technique
万方数据
维普
