Neonatal respiratory distress syndrome(NRDS)is a neonatal respiratory disease caused by insufficient secretion of pulmonary surfactant(PS)due to immature lung tissue,it can cause progressive dyspnea,respiratory failure and other lung symptoms.PS replacement therapy is widely used in clinical practice to treat NRDS.With the deepening of related studies and the continuous enrichment of clinical medication knowledge,more and more clinical optimal drug delivery routes of PS have been reported.This article reviewed the clinical application of PS in NRDS and summarized the latest research results of new PS,administration route,administration timing,administration dose,and administration device,and also discussed the possibility application of PS in other respiratory diseases,to provide the reference for improving the level of clinical application of PS.
关键词
新生儿呼吸窘迫综合征/肺表面活性剂/儿童用药/无创给药技术
Key words
neonatal respiratory distress syndrome/pulmonary surfactant/pediatric drug/non-invasive drug delivery technique
维普
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