世界临床药物2024,Vol.45Issue(2) :213-216.DOI:10.13683/j.wph.2024.02.018

新型口服抗凝药物在晚期慢性肾脏病中的应用进展

Progress in the application of novel oral anticoagulants in advanced chronic kidney disease

任春霞 付晓纯 吴婷婷 周蓉 余自成
世界临床药物2024,Vol.45Issue(2) :213-216.DOI:10.13683/j.wph.2024.02.018

新型口服抗凝药物在晚期慢性肾脏病中的应用进展

Progress in the application of novel oral anticoagulants in advanced chronic kidney disease

任春霞 1付晓纯 1吴婷婷 1周蓉 2余自成1
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作者信息

  • 1. 同济大学附属杨浦医院药学部,上海 200090
  • 2. 同济大学附属杨浦医院肾脏内科,上海 200090
  • 折叠

摘要

晚期慢性肾脏病(chronic kidney disease,CKD)患者静脉血栓栓塞(venous thromboembolism)、心房颤动(atrial fibrillation)的发生风险较高,需接受抗凝治疗.同时,晚期CKD患者出血风险增加使得抗栓治疗复杂化,故需重视其抗凝药物的合理选择和使用.新型口服抗凝药起效快、半衰期短且无需监测实验室指标,其在晚期CKD患者中的应用值得关注.

Abstract

Patients with advanced chronic kidney disease(CKD)have a higher risk of venous thromboembolism and atrial fibrillation and need to receive anticoagulant therapy.At the same time,patients with advanced CKD also have an increased risk of bleeding,which complicates antithrombotic therapy.Therefore,special attention should be paid to the rational selection and use of anticoagulant drugs in advanced CKD patients.The application of novel oral anticoagulant in advanced CKD patients is noteworthy because of the rapid effect,short half-life and no need for laboratory indicator monitoring.

关键词

新型口服抗凝药/晚期慢性肾脏病/终末期肾病/心房颤动/出血

Key words

new oral anticoagulant/advanced chronic kidney disease/end-stage renal disease/atrial fibrillation/hemorrhage

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出版年

2024
世界临床药物
上海医药工业研究院

世界临床药物

CSTPCD
影响因子:0.849
ISSN:1672-9188
参考文献量31
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