Patients with advanced chronic kidney disease(CKD)have a higher risk of venous thromboembolism and atrial fibrillation and need to receive anticoagulant therapy.At the same time,patients with advanced CKD also have an increased risk of bleeding,which complicates antithrombotic therapy.Therefore,special attention should be paid to the rational selection and use of anticoagulant drugs in advanced CKD patients.The application of novel oral anticoagulant in advanced CKD patients is noteworthy because of the rapid effect,short half-life and no need for laboratory indicator monitoring.
关键词
新型口服抗凝药/晚期慢性肾脏病/终末期肾病/心房颤动/出血
Key words
new oral anticoagulant/advanced chronic kidney disease/end-stage renal disease/atrial fibrillation/hemorrhage