The therapeutic effect of self-designed Qufeng Yangxue Runfu liquid bath combined with levocetirizine hydrochloride on maintenance hemodialysis patients with skin itching
Objective To analyze the effects of self-designed Qufeng Yangxue Runfu liquid bath combined with levocetirizine hydrochloride on itchy scratching behavior and calcium and phosphorus metabolism in patients with maintenance hemodialysis(MHD).Methods A total of 80 patients with regular MHD and blood vacuity and wind-driness in our hospital from January 2021 to August 2022 were selected and divided into control group(conventional treatment+levocetirizine hydrochloride)and observation group(conventional treatment+levocetirizine hydrochloride+self-designed Qufeng Yangxue Runfu liquid bath)by random number table method,with 40 cases in each group.Pruritus score,blood calcium,blood phosphorus,parathyroid hormone(PTH),hypersensitive C-reactive protein(hs-CRP),interleukin(IL)-6 and clinical efficacy were compared between the two groups before and after treatment.Results After treatment,the levels of pruritus score,blood phosphorus,PTH,hs-CRP and IL-6 in both groups were decreased(P＜0.05),and the observation group was lower than the control group(P＜0.05).The serum calcium level in both groups were higher than before(P＜0.05),and the observation group was higher than the control group(P＜0.05).The curative effect of observation group was significantly higher than that of control group(87.50％vs 67.50％,P＜0.05).Conclusion Self-designed Qufeng Yangxue Runfu liquid bath combined with levocetirizine hydrochloride has a better effect on skin pruritus in MHD patients,which can effectively relieve pruritus,improve calcium and phosphorus metabolism,and reduce inflammation in vivo.
Qufeng Yangxue Runfu liquidlevocetirizine hydrochloridemaintenance hemodialysisskin itchingcalcium and phosphorus metabolism
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