Research progress on oral prostaglandin in the treatment of pulmonary hypertension
Pulmonary arterial hypertension(PAH)is a progressive and treatable disease characterized by contraction and remodeling of pulmonary arteriole accompanied by increased pulmonary arterial pressure.As PAH progresses,the load on the right ventricle increases,eventually leading to heart failure.Oral prostaglandin(PG)and their analogues can improve the clinical symptoms of PAH,reduce the risk of deterioration or death,delay disease progression,and are relatively safe,convenient,and have high patient compliance.This article reviewed the mechanism and application of oral PG in the treatment of PAH and provided a basis for clinical application.
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