Effect of Yiyuan Qingfei decoction combined with etemicin on severe pneumonia of Qi deficiency lung heat syndrome and its influence on serum SAA,ChE and CHI3L1
Objective To investigate the effect of Yiyuan Qingfei decoction combined with etemicin on patients with severe pneumonia of Qi deficiency lung heat syndrome,and its effects on serum amyloid(SA)A,cholinesterase(ChE),chitinase 3-like protein(CHI3L)1 levels.Methods A total of 100 cases of severe pneumonia of Qi deficiency lung heat syndrome in our hospital from January 2019 to June 2022 were selected and divided into control group and observation group by drawing lots method,with 50 cases in each group.The control group was treated with etimicin,and the observation group was treated with Yiyuan Qingfei decoction on the basis of the control group.The course of treatment was 2 weeks.The efficacy,clinical symptoms,traditional Chinese medicine(TCM)syndrome scores,arterial blood gas,lung function,SAA,ChE and CHI3L1 were compared between the two groups,and the occurrence of adverse reactions during treatment was recorded.Results After treatment,the clinical efficacy of observation group was higher than that of control group,and the improvement time of clinical symptoms was shorter than that of control group(P＜0.05).The levels of lung function index and ChE in observation group were higher than those in control group(P＜0.05),and the levels of TCM syndrome score,SAA and CHI3L1 were lower than those in control group(P＜0.05).No serious adverse reactions occurred in both groups(P＞0.05).Conclusion Yiyuan Qingfei decoction combined with etemicin can effectively improve lung function and serum levels of SAA,ChE and CHI3L1 in the treatment of severe pneumonia with Qi deficiency lung heat syndrome,which is worthy of clinical promotion.
Yiyuan Qingfei decoctionetimicinsevere pneumoniaserum amyloid Acholinesterasechitinase 3-like protein 1
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