世界临床药物2024,Vol.45Issue(8) :864-868.DOI:10.13683/j.wph.2024.08.010

地佐辛联合舒芬太尼对锁骨骨折内固定术术后镇痛的效果观察

The effect of dezocine combined with sufentanil on analgesia after internal fixation of clavicle fractures

薛晓慧 田皇华 冯勇 赵超
世界临床药物2024,Vol.45Issue(8) :864-868.DOI:10.13683/j.wph.2024.08.010

地佐辛联合舒芬太尼对锁骨骨折内固定术术后镇痛的效果观察

The effect of dezocine combined with sufentanil on analgesia after internal fixation of clavicle fractures

薛晓慧 1田皇华 1冯勇 1赵超1
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作者信息

  • 1. 无锡市第八人民医院麻醉科,江苏无锡 214011
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摘要

目的 分析单用舒芬太尼与联合地佐辛对锁骨骨折内固定术术后镇痛的有效性及安全性.方法 选取我院择期行锁骨骨折内固定手术患者60例,随机分为S组和C组,每组30例.两组术后均予静脉自控镇痛,S组予舒芬太尼,C组予舒芬太尼联合地佐辛.记录两组基本情况、术后疼痛视觉模拟评分(visual analogue scale,VAS)[1h(T1)、6h(T2)、12 h(T3)、24h(T4)、48h(T5)]、不良反应发生情况及患者满意度评级.结果 两组基本特征无显著差异(P>0.05).T1、T2时,两组VAS差异无统计学意义(P>0.05);T3、T4、T5时,S组VAS评分显著高于C组(P<0.01).两组不良反应发生率无显著差异(P>0.05).C组患者满意度高于S组.结论 地佐辛联合舒芬太尼用于锁骨骨折内固定术术后镇痛效果明显优于单用舒芬太尼.

Abstract

Objective To analyze the efficacy and safety of sufentanil alone and dezocine combined for postoperative analgesia after internal fixation of clavicular fracture.Methods A total of 60 patients with clavicular fracture undergoing internal fixation in our hospital were randomly divided into group S and group C,with 30 cases in each group.Patients in both groups were given intravenous controlled analgesia,group S was given sufentanil and group C was given sufentanil combined with dezocine.The basic information of the two groups,visual analogue scale(VAS)[1 h(T1),6 h(T2),12 h(T3),24 h(T4),48 h(T5)],occurrence of adverse reactions and patient satisfaction rating were recorded.Results There was no significant difference in basic characteristics between the two groups(P>0.05).At T1 and T2,there was no significant difference in VAS between the two groups(P>0.05).At T3,T4 and T5,VAS scores in group S were significantly higher than those in group C(P<0.01).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).The satisfaction of patients in group C was higher than that in group S.Conclusion The analgesic effect of dezocine combined with sufentanil after internal fixation of clavicular fracture is better than that of sufentanil alone.

关键词

地佐辛/舒芬太尼/锁骨骨折/术后镇痛

Key words

dezocine/sufentanil/clavicle fracture/postoperative analgesia

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出版年

2024
世界临床药物
上海医药工业研究院

世界临床药物

CSTPCD
影响因子:0.849
ISSN:1672-9188
参考文献量2
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