Research progress on the mechanism and potential benefits of iron supplementation in cardiovascular diseases
Iron deficiency affects about a third of the global population and is particularly common in the elderly,women and those with certain chronic conditions.Iron deficiency has adverse effects on coronary artery disease,heart failure,pulmonary hypertension,and patients undergoing cardiac surgery,with approximately 50％of patients with heart failure and pulmonary hypertension having iron deficiency.The widespread use of antithrombotic drugs increases the risk of bleeding,which in turn increases the incidence of hemorrhage-related iron deficiency anemia.Recent studies have shown that iron supplementation can significantly improve quality of life and readmission rates in heart failure patients with reduced ejection fraction.However,the mechanism of its action in various cardiovascular diseases is still unclear.Based on the evidence of the benefits of iron supplementation in various cardiovascular diseases,this article reviewed the mechanism and potential benefits of iron supplementation in various cardiovascular diseases.
iron supplementation therapycardiovascular diseasesheart failure
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