Correlation analysis of blood magnesium with cardiovascular events and all-cause death in hemodialysis patients
Objective To explore the correlation between blood magnesium level in patients with maintenance hemodialysis(MHD)and cardiovascular events and all-cause death.Methods The clinical data of 122 patients treated with MHD in our hospital from January 2021 to January 2023 were retrospectively analyzed,and the patients were divided into high magnesium group(blood magnesium≥0.93 mmol/L,n=67)and low magnesium group(blood magnesium＜0.93 mmol/L,n=55)according to the median blood magnesium level.Kaplan-Meier survival curve was used to compare the cumulative survival rate of the two groups,and Cox regression model was used to analyze the risk factors of all-cause death.Results The levels of serum albumin,prealbumin,magnesium,phosphorus and C-reactive protein were significantly different between the two groups(P＜0.05).The incidence of cardiovascular events and all-cause mortality in low magnesium group were higher than those in high magnesium group(P＜0.05).The cumulative survival rate of low magnesium group was significantly lower than that of high magnesium group(P＜0.01).Univariate Cox regression analysis showed that hypomagnesium was a risk factor for cardiovascular events and all-cause death(P＜0.01).After multifactor correction,hypomagnesium was an independent risk factor for cardiovascular events,but not an independent risk factor for all-cause death(P＞0.05).Conclusion MHD patients with low blood magnesium levels have a higher incidence of cardiovascular events and an increased risk of all-cause death.
blood magnesiummaintenance hemodialysiscardiovascular eventall-cause death
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