Observation on clinical effect of muscovite-infused blood circulation and blood stasis ointment on knee osteoarthritis
Objective To evaluate the efficacy and safety of muscovite-infused blood circulation and blood stasis ointment in the treatment of knee osteoarthritis(KOA).Methods A total of 1 600 KOA patients treated in orthopedics and traumatology departments of 11 hospitals across the country from September 2020 to December 2022 were selected and randomly divided into experimental group(n=1 200,treated with muscovite-infused blood circulation and blood stasis ointment)and control group(n=400,treated with diclofenac diethylamine emulgel)according to a ratio of 3∶1.The course of treatment in both groups was 14 days.Western Ontario and McMaster universities arthritis index(WOMAC)score,visual analogue scale(VAS),traditional Chinese medicine(TCM)syndrome score scale and knee swelling scale score,etc.,and the occurrence of adverse reactions were observed in both groups.Results The total effective rate of the experimental group was higher than that of the control group(86.75％vs 76.50％,P＜0.05).The scores of WOMAC,VAS,TCM syndrome score scale and knee swelling scale in both groups were significantly improved,and the improvement of TCM syndrome score scale and knee swelling scale in the experimental group were better than those in the control group(P＜0.05).During the treatment period,there were no adverse reactions such as drug poisoning or liver and kidney function injury in both groups.Conclusion Muscovite-infused blood circulation and blood stasis ointment can effectively improve the clinical symptoms of KO A patients,with accurate effect and high safety.
muscovite-infused blood circulation and blood stasis ointmentknee osteoarthritisexternal treatment
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