青藤碱用于乳腺癌治疗的机制研究进展
Research progress on the mechanism of sinomenine in the treatment of breast cancer
饶应颖 1李恒宇2
作者信息
- 1. 海军军医大学研究生院,上海 200433
- 2. 海军军医大学第一附属医院甲状腺乳腺外科,上海 200433
- 折叠
摘要
青藤碱是从中药青风藤(Caulis Sinomenii)中提取出的生物碱单体,最初因抗炎、免疫抑制等作用被人们所知,临床上主要治疗类风湿关节炎(rheumatoid arthritis,RA)和自身免疫性疾病.近年来,青藤碱被发现还具有抗乳腺癌(breast cancer,BC)作用,且不良反应较少.该文将对青藤碱用于BC治疗时的作用机制进行综述,以期促进青藤碱抗肿瘤的更多研究的开展,为治疗BC提供理论依据.
Abstract
Sinomenine is an alkaloid monomer extracted from Caulis Sinomenii.Sinomenine was initially known for its anti-inflammatory and immunosuppression,and is mainly used in the treatment of rheumatoid arthritis(RA)and autoimmune diseases.In recent years,sinomenine have been found that it could also play an anti-breast cancer(BC)role through a variety of mechanisms,and less adverse reactions.This article reviewed the mechanism of sinomenine in the treatment of BC,in order to in order to promote the development of more studies of sinomenine in anti-tumor aspects,and provide a theoretical basis for its use in the treatment of BC.
关键词
青藤碱/乳腺癌/抗肿瘤作用/研究进展Key words
sinomenine/breast cancer/antitumor effect/research progress引用本文复制引用
出版年
2024
NETL
NSTL
万方数据