Effects of Sihong Quban decoction combined with photon skin rejuvenation technology on skin lesions in patients with chloasma
Objective To explore the effects of Sihong Quban decoction combined with photon skin rejuvenation technology on the degree of skin lesions and sebum content in patients with chloasma.Methods One-hundred patients diagnosed with chloasma in our hospital from September 2021 to September 2023 were collected and randomly separated into conventional group and combination group,with 50 cases in each group.The conventional group was treated with photon skin rejuvenation technology,while the combination group was treated with Sihong Quban decoction combined with photon skin rejuvenation technology.The clinical efficacy,degree of skin lesions,skin indicators,oxidative stress indicators,serum sex hormone indicators,and adverse reactions were observed after treatment.Results After treatment,the total effective rate of the combination group was 96.00％,the conventional group was 76.00％,and the combination group was obviously higher than the conventional group(P＜0.05).The skin color score,skin lesion area score,total skin lesion score,sebum content of skin lesions,pigmentation,pores,wrinkles,melasma area severity index score,malonaldehyde,follicle-stimulating hormone,luteinizing hormone,and estradiol levels of the two groups were obviously reduced compared to before treatment,and the above indicators(except for sebum content)in the combination group were obviously lower than those in the conventional group(P＜0.05).There was no obvious difference in sebum content between the two groups(P＞0.05).The skin moisture content,skin elasticity index,superoxide dismutase(SOD)and catalase(CAT)levels in both groups were obviously increased compared to before treatment(P＜0.05),and the combination group had obviously higher skin moisture content,skin elasticity index,SOD and CAT levels than the conventional group(P＜0.05).There was no significant difference in adverse reaction rate between the two groups during treatment(P＞0.05).Conclusion Sihong Quban decoction combined with photon skin rejuvenation technology can improve clinical efficacy,reduce skin lesions and oxidative stress response,improve skin condition,and regulate serum sex hormone levels in patients with chloasma.
Sihong Quban decoctionphoton skin rejuvenation technologychloasmadegree of skin lesionsebum content
万方数据
