The analysis of therapeutic effect of Dengtaiye granules combined with glycine theophylline sodium in the treatment of asthmatic bronchitis
Objective To explore the therapeutic effect of Dengtaiye granules combined with glycine theophylline sodium sustained-release tablets in the treatment of acute exacerbation of chronic asthmatic bronchitis.Methods 106 patients with acute exacerbation of chronic asthmatic bronchitis admitted to Shiyan Taihe Hospital from April 2021 to December 2023 were selected and divided into the control group and the treatment group,and 53 cases in each group.The control group was treated with glycine theophylline sodium sustained-release tablets,and the treatment group was treated with Dengtaiye granules combined with glycine theophylline sodium sustained-release tablets.The therapeutic effects,the improvement time of traditional Chinese medicine symptoms,serum inflammation indicators,and adverse reactions between two groups were compared after 7 days of treatment.Results The total effective rate of the treatment group was higher than that of the control group(96.23％vs 84.91％,P＜0.05).The improvement time of cough,phlegm accumulation,wheezing,facial redness and irritability,and dry stools in the treatment group was shorter than that in the control group(P＜0.05).After treatment,C-reactive protein,interleukin(IL)-6,IL-17,and tumor necrosis factor-a were decreased in the two groups(P＜0.05),and the treatment group were lower than those in the control group(P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion Dengtaiye granules combined with glycine theophylline sodium sustained-release tablets can achieve ideal therapeutic effects in the treatment of acute exacerbation of chronic asthmatic bronchitis.It can quickly improve the traditional Chinese medicine symptoms of patients,effectively reduce the inflammatory response in the body,and has high safety.
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