Micromeritic and stability studies on Xiahuang Granule extracts
Objective To evaluate the preformulation studies, such as micromeritic and stability studies on Xiahuang Granule extracts and to provide a reference for the design of fine particle formulation of design. Methods Powder micromeritics major parameters of Xiahuang Granule extracts, such as bulk density, angle of repose, dissolve resistance, pH value, moisture absorption, and critical relative humidity were studied. Aloin as the main active ingredient in the prescription was determined to compare the effects of high temperature, high humidity, and strong light on Xiahuang Granule extract, such as bulk density, angle of repose, dissolve resistance, pH value, moisture absorption, and critical relative humidity were studied. Results Xiahuang Granule extracts had the good water solubility with repose angle greater than 45 degrees, but poor mobility and weak acidity. The critical relative moisture of it was72%. Xiahuang Granule extracts had not been resistant to high temperature, moisture absorption, and lightfast properties. Conclusion The powder of Xiahuang Granule extracts should be stored up on sealed, dark, and dry place.
NETL
NSTL
万方数据
维普
