Clinical observation of Kuntai Capsules combined with zolpidem in treatment of sleep disorder of climacteric syndrome with kidney deficiency and liver depression syndrome
Objective To explore the clinical effect of Kuntai Capsules combined with zolpidem in treatment of sleep disorder of climacteric syndrome with kidney deficiency and liver depression syndrome.Methods Patients(120 cases)with sleep disorder of climacteric syndrome with kidney deficiency and liver depression syndrome in Affiliated Hospital of Jining Medical University from January 2022 to December 2022 were randomly divided into control and treatment group,and each group had 60 cases.Patients in the control group were po administered with Zolpidem Tartrate Tablets before bed,the initial dose was 5 mg/time,once daily,and the maximum dose was 10 mg.Patients in the treatment group were po administered with Kuntai Capsules on the basis of the control group,4 grains/time,three times daily.Patients in two groups were treated for 12 weeks.After treatment,the clinical evaluations was evaluated,the TCM syndrome score and PSQI score,and the FSH,LH,and E2 levels in two groups before and after treatment were compared.Results After treatment,the clinical effective rate of the treatment group was significantly higher than that of the control group(98.33% vs 88.33% ,P<0.05).After treatment,the TCM syndrome score and PSQI score in two groups were significantly lower than those before treatment(P<0.05),and these scores in the treatment group were significantly lower than those of the control group(P<0.05).After treatment,the levels of FSH and LH in two groups were significantly lower than those before treatment,while the level of E2 was significantly higher(P<0.05),and the level of sex hormones in the treatment group was significantly better than that in the control group(P<0.05).Conclusion Kuntai Capsules combined with zolpidem in the treatment of sleep disorder of climacteric syndrome with kidney deficiency and liver depression syndrome can effectively regulate the level of sex hormones,improve TCM syndrome and improve sleep quality.
Kuntai CapsulesZolpidem Tartrate Tabletssyndrome of kidney deficiency and liver depressionClimacteric syndromesleep disorderPSQIFSHLH
NETL
NSTL
万方数据
维普
