Clinical study on Guilong Kechuanning Tablets combined with budesonide in treatment of acute bronchitis in children
Objective To investigate the therapeutic effect of Guilong Kechuanning Tablets combined with budesonide in treatment of acute bronchitis in children.Methods Children(148 cases)with acute bronchitis in Yuncheng Central Hospital from March 2021 to March 2023 were randomly divided into control(74 cases)and treatment(74 cases)group.Children in the control group were administered with Budesonide Suspension for inhalation,1 mL added into normal saline 2 mL,once daily.Children in the treatment group were po administered with Guilong Kechuanning tablets on the basis of the control group,4 tablets/time,twice daily.Children in two groups were treated for 7 d.After treatment,the clinical evaluation was evaluated,and the time of symptom relief,the levels of WBC,CRP and IL-17 in two groups before and after treatment were compared.Results After treatment,the clinical effective rate of the treatment group was 93.24% ,which was significantly higher than that of the control group(81.08% ,P<0.05).After treatment,the disappearance time of cough,body temperature and sputum in the treatment group were shorter than those in the control group(P<0.05).After treatment,the levels of WBC,CRP,and IL-17 in both groups were significantly lower than those before treatment(P<0.05),and the reduction range in the treatment group was significantly greater than that in the control group(P<0.05).Conclusion Guilong Kechuanning Tablets combined with budesonide in treatment of acute bronchitis in children can help children with acute bronchitis quickly control clinical symptoms and reduce inflammatory reaction in vivo with good efficacy and safety.
Guilong Kechuanning tabletsBudesonide Suspension for inhalationacute bronchitisWBCCRP
NETL
NSTL
万方数据
维普
