Clinical observation on Qihuang Jiangtang Capsules combined with liraglutide in treatment of type 2 diabetes mellitus with poor glycemic control
Objective To investigate the clinical efficacy of Qihuang Jiangtang Capsules combined with Liraglutide Injection in treatment of type 2 diabetes mellitus with poor glycemic control.Methods Patients(85 cases)with type 2 diabetes mellitus with poor glycemic control in Xinxiang Central Hospital from November 2021 to December 2022 were divided into the control group(42 cases)and the treatment group(43 cases)according to random number tablet method.Patients in the control group were sc administered with Liraglutide Injection,starting at 0.6 mg/time,once daily,if there were no adverse reactions after one week,the dosage was increased to 1.2 mg/time.Patients in the treatment group were po administered with Qihuang Jiangtang Capsules on the basis of the control group,6 grains/time,three times daily.Patients in two groups were treated for 12 weeks.After treatment,the clinical efficacies were evaluated,and the Quality of life,blood glucose indicators,and insulin related indicators in two groups were compared.Results After treatment,the total effective rate of the control group was 73.81% ,while the total effective rate of the treatment group was 93.02% .The clinical total effective rate of the treatment group was higher than that of the control group(P<0.05).After treatment,the scores of all dimensions of DMQLS in two groups decreased(P<0.05),and the scores of all dimensions of DMQLS in the treatment group were lower than those in the control group(P<0.05).After treatment,FBG,2 h PG,and HbAlc in two groups were decreased(P<0.05),and FBG,2 h PG,and HbAlc in the treatment group were lower than those in the control group(P<0.05).After treatment,FINS,HOMA-β,and HOMA-IR in two groups increased(P<0.05),and FINS,HOMA-β,and HOMA-IR in the treatment group were higher than those in the control group(P<0.05).Conclusion Qihuang Jiangtang Capsules combined with Liraglutide Injection in treatment of type 2 diabetes mellitus with poor glycemic control,which can improve the quality of life of patients,effectively control blood sugar and improve insulin levels.
NETL
NSTL
万方数据
维普
