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基于层次属性模型的术后用地佐辛注射液合理性评价

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目的 建立术后用地佐辛注射液合理性评价标准,分析其不合理用药情况,为临床合理、规范应用该药物提供参考依据。方法 参考药品说明书、专家共识和指南等制定术后用地佐辛注射液合理性评价细则,随机抽取安徽医科大学附属亳州医院 2023年 1~6 月科室用药频度(DDDs)排名前 5 位的 252 例术后用地佐辛注射液的病历,应用属性层次模型(AHM)对其进行合理性评价。结果 252 例病历中,病历评分(MRS)≥90 分的优秀病历 103 例(占 40。87%),75 分≤MRS<90分的良好病历 12 例(占 4。76%),60 分≤MRS<75 分的合格病历 41 例(占 16。27%)以及MRS<60 分的不合格病历 96 例(占 38。10%)。不合理类型主要表现为无适应证 48 例次(占 28。40%),用法用量 43 例次(占 25。44%),用药疗程 36 例次(占21。30%),特殊人群用药 22 例次(占 13。02%),联合用药 10例次(占 5。92%)及禁忌证 5例次(2。96%)。结论 基于AHM法制定的术后用地佐辛注射液评价方法切实可行,评价结果显示安徽医科大学附属亳州医院术后用地佐辛注射液不合理用药情况较差,医院应进一步加强其医嘱点评、用药管理,提高临床用药合理性。
Rationality evaluation of postoperative use of Dizocine Injection based on hierarchical attribute model
Objective To establish rational evaluation standard of postoperative use of Dizocine Injection,and the unreasonable drug use was analyzed to provide a reference for the rational clinical application of this drug.Methods To formulate the rational dosing evaluation system based on drug specification,expert recommendations,guidelines,and other relevant documents.The medical records of 252 patients with postoperative Dizocine Injection,who ranked the top 5 in department use frequency(DDDs)in Bozhou Hospital affiliated to Anhui Medical University from January to June 2023,were randomly selected,and the rationality of them was evaluated by attribute hierarchy model(AHM).Results Among the 252 medical records,103 excellent medical records(40.87% )had a medical record score(MRS)≥90,and 12 good medical records(4.76% )had a medical record score of 75≤MRS<90.There were 41 qualified medical records(16.27% )with 60≤MRS<75 scores,and 96 unqualified medical records(38.10% )with MRS<60 scores.The irrational type mainly showed no indication 48 times(28.40% ),usage and dosage 43 times(25.44% ),treatment course 36 times(21.30% ),special population 22 times(13.02% ),combined use 10 times(5.92% )and contraindication 5 times(2.96% ).Conclusion The evaluation method of Dizocine Injection for postoperative use formulated based on AHM method is feasible,and the evaluation results show that the situation of irrational use of Dizocine Injection for postoperative use in Bozhou Hospital affiliated to Anhui Medical University is poor.The hospital should further strengthen its medical order comments and medication management to improve the rationality of clinical use.

Dizocine Injectionreasonable applicationattribute hierarchical modelindicationsusage and dosagecourse of medication

李华峰、夏茹楠、鲁宁、陈慧娟、张红、梁海

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安徽医科大学附属亳州医院 药学部,安徽 亳州 236800

地佐辛注射液 合理性评价 属性层次模型 适应证 用法用量 用药疗程

安徽省重点研发计划安徽医科大学科研项目

2022e070200662021xkj095

2024

现代药物与临床
天津药物研究院,中国药学会

现代药物与临床

CSTPCD
影响因子:1.179
ISSN:1674-5515
年,卷(期):2024.39(1)
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