Objective To explore the therapeutic effect of Longqi Weikang Tablets combined with esomeprazole in treatment of gastric ulcers.Methods A total of 94 patients with gastric ulcer who received treatment in Zhengzhou Seventh People's Hospital from January 2022 to June 2023 were randomly divided into control group(47 cases)and treatment group(47 cases).Patients in the control group were po administered with Esomeprazole Enteric Capsules,20 mg/time,twice daily.Patients in the treatment group were po administered with Longqi Weikang Tablets on the basis of the control group,3 tablets/time,three times daily.Patients in two groups were treated for 4 weeks.The clinical efficacy,ulcer healing,duration of clinical symptoms and the levels of gastrin,C-reactive protein(CRP)and interleukin-17(IL-17)in two groups were observed.Results After treatment,the total effective rate of treatment group was 95.74%,which was significantly higher than that of control group(80.85%,P<0.05).After treatment,the ulcer healing rate in treatment group was 87.23%,which was significantly higher than that in control group(70.21%)(P<0.05).The disappearance time of abdominal pain,acid reflux and belching in treatment group was significantly shorter than that in control group(P<0.05).After treatment,the levels of gastrin,CRP,and IL-17 in two groups were significantly decreased compared with before treatment(P<0.05).After treatment,the levels of gastrin,CRP,and IL-17 in treatment group were lower than those in control group(P<0.05).Conclusion Longqi Weikang Tablets combined with esomeprazole has good clinical efficacy in treatment of gastric ulcers,and can effectively promote ulcer healing,shorten the time for clinical symptom disappearance,improve the levels of gastrointestinal hormones and inflammatory indicators in the body,which has no obvious adverse drug reactions.
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