Clinical study on Baotailing Capsules combined with atosiban in treatment of advanced threatened abortion
Objective To observe the clinical effect of Baotailing Capsules combined with Atosiban Acetate Injection in treatment of advanced threatened abortion.Methods Women(100 cases)with advanced threatened abortion in Handan Maternal and Child Health Hospital from March 2020 to December 2021 were divided into control and treatment groups according to the random drawing method,and each group had 50 cases.Women in the control group were iv administered with Atosiban Acetate Injection,the first infusion was 6.75 mg(time>1 min,0.9 mL/6.75 mg),followed by 5 mL/37.5 mg(total 20 mL)dissolved in 180 mL glucose by intravenous drip(24 mL/h for 3 h),and 3 h later by intravenous drip at 8 mL/h until the contraction inhibition effect was achieved.Women in the treatment group were po administered with Baotailing Capsules on the basis of the control group,3 grains/time,three times daily.Patients in two groups were treated for 2 weeks.After treatment,the clinical efficacies,symptom improvement time,serum sex hormone levels,and maternal and infant outcomes in two groups were compared.Results After treatment,the total effective rate of the treatment group was higher than that of the control group(P<0.05).The improvement time of lumbar acid,abdominal pain and vaginal bleeding in the treatment group were shorter than those in the control group(P<0.05).After treatment,the serum levels of hCG,P,and E2 in two groups were higher than before treatment(P<0.05),and the serum sex hormone levels in the treatment group were higher than those in the control group(P<0.05).After treatment,the number of full-term eliveries in the treatment group was higher than that in the control group,but the number of natural abortions was lower than that in the control group(P<0.05).Conclusion Baotailing Capsules combined with Atosiban Acetate Injection is effective in treatment of advanced threatened abortion,can improve clinical symptoms,adjust sex hormone levels,improve maternal and infant outcomes.
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