Clinical study on Hongjin Xiaojie Capsules combined with Levonorgestrel-Releasing Intrauterine System in treatment of uterine fibroids
Objective To investigate the clinical efficacy of Hongjin Xiaojie Capsules combined with Levonorgestrel-Releasing Intrauterine System in treatment of uterine fibroids.Methods Women(96 cases)with uterine fibroids in the 7th People's Hospital of Zhengzhou from July 2021 to January 2023 were divided into control and treatment groups according to the random drawing method,and each group had 48 cases.Women in the control group received Levonorgestrel-Releasing Intrauterine System,and placed Levonorgestrel-Releasing Intrauterine System 3—5 d after menstruation,after shaving most of the endometrial,and the course of treatment was 3 months.Women in the treatment group were po administered with Hongjin Xiaojie Capsules on the basis of the control group,4 grains/time,three times daily.Patients in two groups were treated for 3 months.After treatment,the clinical efficacies,menstrual blood loss,uterine volume,fibroid volume,quality of life,and serum sex hormone level in two groups were compared.Results After treatment,the total effective rate of the treatment group was higher than that of the control group(P<0.05).After treatment,the amount of menstrual bleeding,uterine volume,and fibroid volume,and the serum levels of LH,FSH,P,and E2 in the two groups were lower than before treatment,the material living status score,physical function score,psychological function score,and social function score of two groups were higher than before treatment(P<0.05),and the above indexes in the treatment group were better than those in the control group(P<0.05).Conclusion Hongjin Xiaojie Capsules combined with Levonorgestrel-Releasing Intrauterine System in treatment of uterine fibroids can reduce the volume of uterus and fibroids,reduce menstrual bleeding,improve quality of life,and improve sex hormone levels.
Hongjin Xiaojie CapsulesLevonorgestrel-Releasing Intrauterine Systemuterine fibroidsamount of menstrual bleedinguterine volumePE2
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