Clinical study on Yinhua Miyanling Tablets combined with norfloxacin in treatment of type Ⅲ prostatitis
Objective To investigate the clinical effect of Yinhua Miyanling Tablets combined with Norfloxacin Capsules in treatment of type Ⅲ prostatitis.Methods Patients(83 cases)with type Ⅲ prostatitis in Shanghai Punan Hospital of Pudong New Area from January 2021 to December 2022 were divided into the control group(41 cases)and the treatment group(42 cases)according to random number tablet method.Patients in the control group were po administered with Norfloxacin Capsules,0.4 g/time,twice daily.Patients in the treatment group were po administered with Yinhua Miyanling Tablets on the basis of the control group,4 tablets/time,four times daily.Patients in two groups were treated for 8 weeks.The clinical efficacy,condition,urodynamic indexes,and serum inflammatory factors in two groups were compared.Results After treatment,the total effective rate of the treatment group(97.62%)was significantly higher than 80.49% of the control group,and the difference was statistically significant(P<0.05).After treatment,NIH-CPSI score of two groups was significantly lower than that before treatment(P<0.05),and NIH-CPSI score of the treatment group was significantly lower than that of the control group(P<0.05).After treatment,the maximum urine flow rate increased in two groups,but the residual urine volume in two groups decreased(P<0.05).And the maximum urine flow rate in the treatment group was higher than that in the control group,but the residual urine volume in the treatment group was lower than that in the control group(P<0.05).After treatment,the serum levels of IL-8,IL-10,and TNF-α in two groups were significantly decreased compared with that before treatment(P<0.05),and the serum levels of IL-8,IL-10,and TNF-α in the treatment group were lower than those in the control group(P<0.05).Conclusion Yinhua Miyanling Tablets combined with Norfloxacin Capsules has good efficacy in treatment of type Ⅲprostatitis,which can effectively alleviate the condition,improve urodynamics,and reduce the degree of inflammatory response.
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