Objective To investigate the clinical effect of Danshen Injection combined with Ticagrelor Tablets in treatment of acute myocardial infarction.Methods Patients(72 cases)with acute myocardial infarction in Yixing People's Hospital from February 2020 to August 2023 were divided into control and treatment groups according to the random number table method,and each group had 36 cases.Patients in the control group were po administered with Ticagrelor Tablets,1 tablet/time,twice daily.Patients in the treatment group were iv administered with Danshen Injection on the basis of the control group,10 mL added into 300 mL glucose injection,once daily.Patients in two groups were treated for 2 weeks.The clinical efficacies,the degree of chest pain,the cardiac function indicators,and the serum indicators in two groups were compared.Results The total effective rate of the treatment group was 94.44%,while the total effective rate of the control group was 77.78%,with a significant difference between the groups(P＜0.05).After treatment,the frequency and duration of chest pain attacks in both groups were lower than those before treatment(P＜0.05),and the indexes in the treatment group were significantly lower than those in the control group(P＜0.05).After treatment,LVEF,SV,and CI of two groups were higher than before treatment(P＜0.05),and the cardiac function indicators of the treatment group were higher than those of the control group(P＜0.05).After treatment,the levels of Apo-A in two groups significantly increased,while the levels of hs-cTn and Lp-PLA2 in two groups significantly decreased(P＜0.05).The levels of Apo-A in the treatment group was higher than that in the control group,while the levels of hs-cTn and Lp-PLA2 in the treatment group were lower than those in the control group(P＜0.05).Conclusion Danshen Injection combined with Ticagrelor Tablets can improve the efficacy of acute myocardial infarction,reduce the degree of chest pain,improve heart function,and alleviate myocardial damage.
Danshen InjectionTicagrelor Tabletsacute myocardial infarctionfrequency of chest pain attacksLVEFCIApo-Ahs-cTnLp-PLA2
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