Research progress on mechanism of ligustrazine in prevention and treatment of acute pancreatitis
Acute pancreatitis is characterized by fatal,pathogenic and high mortality.Ligustrazine can play a role in prevention and treatment of acute pancreatitis by promoting cell apoptosis,correcting microcirculation disorders,alleviating inflammatory reactions,reducing lipid peroxidation,inhibiting LPS/TLR4 signaling pathways,and protecting the intestinal mucosal barrier function.This article summarizes the mechanism of ligustrazine in prevention and treatment of acute pancreatitis,providing reference for the treatment of acute pancreatitis.
ligustrazineacute pancreatitiscell apoptosismicrocirculation disorderinflammatory reactionlipid peroxidationintestinal mucosal barrier function
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