Clinical observation on Tongtian Oral Solution combined with betasteine in treatment of vestibular migraine
Objective To explore the clinical efficacy of Tongtian Oral Solution combined with Betahistine Hydrochloride Tablets in treatment of vestibular migraine.Methods Patients(110 cases)with vestibular migraine in Shanghai Baoshan District Renhe Hospital from January 2020 to December 2022 were divided into control and treatment groups according to the random number table metho,and each group had 55 cases.Patients in the control group were po administered with Betahistine Hydrochloride Tablets,2 tablets/time,twice daily.Patients in the treatment group were po administered with Tongtian Oral Solution on the basis of the control group,Tongtian Oral Solution was taken orally 10 mL at 0 h,1 h,2 h,and 4 h on the first day,then 10 mL every 6 h,then 10 mL/time,three times daily.Patients in two groups were treated for 2 months.The clinical efficacies,the blood flow velocity of vertebrobasilar artery,the degree of headache,the degree of vertigo,the number of monthly episodes of symptoms,and sleep quality in two groups were compared.Results The improvement rate of the treatment group was 83.64%,which was significantly higher than 65.45%of the control group(P<0.05).After treatment,the average blood flow velocity of LVA,RVA,and BA,the VAS scores and DHI scores,the monthly frequency of symptoms and PSQI score of two groups were significantly decreased(P<0.05),and the indexes of the treatment group were lower than those of the control group(P<0.05).Conclusion Tongtian Oral Liquid combined with Betahistine Hydrochloride Tablets has a good effect on the treatment of vestibular migraine,which can improve vertebrobasilar artery stenosis,effectively reduce the degree of headache and vertigo,reduce the frequency of symptoms and improve the sleep quality of patients.
Tongtian Oral LiquidBetahistine Hydrochloride Tabletsvestibular migraineblood flow velocity of vertebrobasilar arteryVAS scoreDHI scorenumber of monthly episodes of symptomsPSQI score
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