Clinical study on Qingke Pingchuan Granules combined with compound methoxyphenamine hydrochloride in treatment of postinfectious cough(phlegm heat obstruction of the lung syndrome)
Objective Observe the clinical efficacy of Qingke Pingchuan Granules combined with compound methoxyphenamine in treatment of postinfectious cough(phlegm heat obstruction of the lung syndrome).Methods A total of 178 patients with postinfectious cough(phlegm heat obstruction of the lung syndrome)in Beijing University of Chinese Medicine Third Affiliated Hospital,Beijing Shunyi Hospital of Traditional Chinese Medicine,Chinese People's Liberation Army Air Force Characteristic Medical Center,Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University,the Fourth Medical Center of the General Hospital of the People's Liberation Army of China,the Seventh Medical Center of the General Hospital of the People's Liberation Army of China,and the Eighth Medical Center of the General Hospital of the People's Liberation Army of China from April 2023 to June 2023 were randomly divided into control(88 cases)and treatment(90 cases)group.Patients in the control group were po administered with Compound Methoxyphenamine Hydrochloride Capsules,2 grains/time,three times daily.Patients in the treatment group were po administered with Qingke Pingchuan Granules on the basis of the control group,1 bag/time,three times daily.Patients in two groups were treated for 7 d.After treatment,the clinical evaluations were evaluated,the cough severity scores,cough relief and disappearance time,the levels of inflammatory indicators WBC,IL-6 and CRP in two groups before and after treatment were compared.Results After treatment,the clinical effective rate of the treatment group was 97.73%,which was significantly higher than that of the control group(89.77%,P<0.05).After treatment,the cough degree in two groups was significantly improved(P<0.05),and the improvement of cough score on the 7th day in the treatment group was significantly stronger than that in the control group(P<0.05).After treatment,the relief time and disappearance time of cough symptoms in the treatment group were significantly shorter than that in the control group(P<0.05).After treatment,the levels of WBC,IL-6 and CRP in two groups were significantly decreased,and the levels of IL-6 and CRP in the treatment group were significantly improved(P<0.05).Conclusion Qingke Pingchuan Granules combined with compound methoxyphenamine hydrochloride can significantly improve the clinical effective rate,improve the degree of cough,promote the relief and disappearance of cough symptoms,and reduce the level of inflammation.
Qingke Pingchuan GranulesCompound Methoxyphenamine Hydrochloride Capsulespostinfectious coughphlegm heat obstruction of the lung syndromecough severity scoresWBCCRP
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