Clinical study on Jingling Oral Liquid combined with aripiprazole in treatment of attention deficit and hyperactivity disorder in children
Objective To explore the clinical therapeutic effect of Jingling Oral Liquid combined with Aripiprazole Tablets on attention deficit and hyperactivity disorder in children.Methods Children(60 cases)with attention deficit and hyperactivity disorder in First Hospital of Qinhuangdao from January 2022 to December 2022 were divided into control group(30 cases)and treatment group(30 cases)according to the random number table method.Children in the control group were po administered with Aripiprazole Tablets at night,initial dose 1 tablet/time,once daily,after 2 weeks of medication,the drug dosage gradually increased based on the actual efficacy and tolerance,with a maximum dose not exceeding 3 tablets daily.Children in the treatment group were po administered with Jingling Oral Liquid on the basis of the control group,1 piece/time,twice daily.Children in two groups were treated for 8 weeks.The clinical efficacies,the symptoms,hyperactivity disorder,attention,and serum indicators in two groups were compared.Results The total effective rate of the treatment group(93.33%)was significantly higher than 73.33%of the control group(P<0.05).After treatment,the SNAP-IV score,PSQ score and NCT error rate in two groups were significantly decreased,and serum PRL,S100-β,and 25-hydroxyvitamin D in two groups were significantly increased(P<0.05),and the changes of indexes in treatment group were better than those in the control group(P<0.05).Conclusion The clinical effect of Jingling oral liquid combined with Aripiprazole Tablets is significant,which can effectively improve the clinical symptoms of children and increase their attention,and regulate serum factors.
Jingling Oral LiquidAripiprazole Tabletsattention deficit and hyperactivity disorder in childrenSNAP-IV scorePSQ scoreNCT error ratePRLS100-β25-hydroxyvitamin D
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