Clinical study of Pulean Capsules combined with tamsulosin in treatment of chronic prostatitis
Objective To observe the clinical efficacy of Pulean Capsules combine with Tamsulosin Hydrochloride Sustained-release Capsules in treatment of chronic prostatitis.Methods Patients(200 cases)with chronic prostatitis in the Fifth Affiliated Hospital of Zhengzhou University from April 2020 to May 2022 were divided into control group(100 cases)and treatment group(100 cases)according to the random number table method.Patients in the control group were po administered with Tamsulosin Hydrochloride Sustained-release Capsules,1 grain/time,once daily.Patients in the treatment group were po administered with Pulean Capsules on the basis of the control group,4—6 grains/time,three times daily.Patients in two groups were treated for 2 weeks.After treatment,the clinical efficacies,the improvement in condition,urodynamic indicators,and prostate fluid cytokines in two groups were compared.Results After treatment,the total effective rate of the treatment group was 96.00%,which was higher than the total effective rate of the control group of 85.00%(P<0.05).After treatment,NIH-CPSI scores and IPSS scores of two groups were significantly decreased,the residual urine volume were decreased,but the Qave and Qmax were increased,the levels of IL-6,TNF-α,PGE2,IL-8,and IL-12 in prostatic fluid of two groups were significantly decreased(P<0.05),and the improvement in condition,urodynamic indicators,and prostate fluid cytokines of the treatment group were significantly better than those of the control group(P<0.05).Conclusion Pulean Capsules combine with Tamsulosin Hydrochloride Sustained-release Capsules in treatment of chronic prostatitis,which can effectively improve the clinical symptoms of patients,reduce levels of inflammatory factors,and improve urodynamics.
NETL
NSTL
万方数据
