Clinical study on Binghuang Fule Ointment combined with Calcipotriol Ointment in treatment of psoriasis vulgaris
Objective To explore the clinical efficacy of Binghuang Fule Ointment combined with Calcipotriol Ointment in treatment of psoriasis vulgaris.Methods Patients(88 cases)with psoriasis vulgaris in Taiyuan Central Hospital from August 2021 to August 2023 were divided into control and treatment groups according to the computer random arrangement method,and each group had 44 cases.Patients in the control group was given topical Calcipotriol Ointment,once in the morning and once in the evening every day.Patients in the treatment group were topical application of Binghuang Fule Ointment on the basis of the control group,three times daily.Patients in two groups were treated for 8 weeks.The clinical efficacies,the symptom relief time,skin condition,skin condition,and T lymphocytes in two groups were compared.Results After treatment,the total effective rate of the treatment group was 93.18%,significantly higher than 77.27%of the control group of,with a statistically significant difference(P<0.05).After treatment,the relief time for itching,skin lesions,and erythema and papules in the treatment group was significantly shorter than those in the control group(P<0.05).After treatment,the PASI scores,the number of superficial dermal blood vessels,the thickness of the spinous layer,and the Th1 and Th1/Th2 levels of two groups were smaller than those before treatment,while the Th2 levels in two groups were higher than those before treatment(P<0.05).And after treatment,the skin condition,skin condition,and T lymphocytes of the treatment group were better than those of the control group(P<0.05).Conclusion The combination of Binghuang Fule Ointment and Calcipotriol Ointment can improve the therapeutic effect of psoriasis vulgaris,alleviate clinical symptoms,improve skin condition,and regulate Th1/Th2 balance.
Binghuang Fule OintmentCalcipotriol Ointmentpsoriasis vulgarisrelief time for erythematous papulesPASI scorenumber of superficial dermal blood vesselthickness of the spinous layerTh1/Th2
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