Research progress on protection of puerarin against myocardial ischemia-reperfusion injury
Acute myocardial infarction is a common critical condition of the cardiovascular system in clinical practice,but the reperfusion process often leads to myocardial ischemia-reperfusion injury.Puerarin is an isoflavone compound extracted from Puerariae Radix,with a wide range of pharmacological effects.Puerarin can alleviate myocardial ischemia-reperfusion injury through mechanisms such as anti-oxidative stress,anti-inflammatory response,inhibition of autophagy,and inhibition of ferroptosis.This article summarizes the mechanism of puerarin in protecting against myocardial ischemia-reperfusion injury,in order to provide reference for the clinical treatment of acute myocardial infarction with puerarin.