Clinical study on Qishen Yiqi Dropping Pills combined with felodipine in treatment of heart disease and angina pectoris
Objective To explore the clinical s efficacy of Qishen Yiqi Dropping Pills combined with felodipine in treatment of heart disease and angina pectoris.Methods Patients(90 cases)with heart disease and angina pectoris in the second affiliated Hospital of Wannan Medical College from June 2022 to June 2023 were divided into control(45 cases)and treatment(45 cases)group according to drug use.Patients in the control group were po administered with Felodipine Sustained Release Tablets,5 mg/time,once daily.Patients in the treatment group were po administered with Qishen Yiqi Dropping Pills on the basis of the control group,1 bag/time,three times daily.Patients in two groups were treated for 14 d.After treatment,the clinical evaluations were evaluated,the symptom relief time,CK-MB,CK,LDH,6MWD,MMSE and GRACE in two groups before and after treatment were compared.Results After treatment,the clinical effective rate of the treatment group was 93.33%,which was significantly higher than that of the control group(80.00%,P<0.05).After treatment,the time of symptom improvement in the treatment group was significantly earlier than that in the control group(P<0.05).After treatment,the levels of CK-MB,CK,and LDH in myocardial enzymes in two groups were significantly lower than those before treatment(P<0.05),and which in the treatment group were significantly lower than those in the control group(P<0.05).After treatment,the 6MWD test and MMSE score were significantly increased,while the GRACE score was significantly decreased in two groups(P<0.05),and the 6MWD test,MMSE score and GRACE score in the treatment group were significantly better than those in the control group(P<0.05).Conclusion The synergistic treatment of Qishen Yiqi Dropping Pills and felodipine can significantly improve the symptoms of angina pectoris,enhance myocardial blood supply,effectively improve exercise tolerance,mental state,and reduce the risk of prognosis.
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