Objective To investigate the clinical effect of Pingfeng Shengmai Capsules combined with Isosorbide Mononitrate Tablets in treatment of angina pectoris of coronary heart disease.Methods Patients(120 cases)with angina pectoris of coronary heart disease in the People's Hospital Yizhou from January 2022 to June 2023 were divided into control and treatment groups according to the computer random arrangement method,and each group had 60 cases.Patients in the control group were po administered with Isosorbide Mononitrate Tablets,1 tablet/time,twice daily.Patients in the treatment group were po administered with Pingfeng Shengmai Capsules on the basis of the control group,3 grains/time,three times daily.Patients in two groups were treated for 1 month.After treatment,the efficacies of angina pectoris and electrocardiographic were evaluated,and the angina pectoris pain symptoms,cardiac function indicators,and serum indicators in two groups were compared.Results After treatment,the total effective rate of angina pectoris in the treatment group was higher than that in the control group,with a significant difference(93.33%vs 80.00%,P<0.05).After treatment,the total effective rate of electrocardiogram in the treatment group was higher than that in the control group,with a significant difference(85.00%vs 70.00%,P<0.05).After treatment,pain degree,duration,and frequency in two groups were significantly decreased(P<0.05),and the angina pectoris symptoms in the treatment group were lower than those in the control group(P<0.05).After treatment,EF,CI,and SV in two groups were higher than those before treatment(P<0.05),and EF,CI,and SV in the treatment group were higher than those in the control group(P<0.05).The serum levels of cTnI,H-FABP,TRAF6,and Lp-PLA2 in two groups were lower than those before treatment(P<0.05),and the serum indexes in the treatment group were lower than those in the control group(P<0.05).Conclusion Pingfeng Shengmai Capsules combined with Isosorbide Mononitrate Tablets can significantly improve the efficacy of angina pectoris and electrocardiogram,reduce the symptoms of angina pectoris,improve heart function and reduce myocardial inflammation.
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