Objective To explore the curative effect of Xinmaitong Capsules combined with Rosuvastatin Calcium Tablets in treatment of senile hyperlipidemia.Methods Patients(82 cases)with senile hyperlipidemia in Huainan Oriental Hospital Group General Hospital from May 2021 to June 2023 were divided into control and treatment groups according to the random number table method,and each group had 41 cases.Patients in the control group were po administered with Rosuvastatin Calcium Tablets,1 tablet/time,once daily.Patients in the treatment group were po administered with Xinmaitong Capsules on the basis of the control group,4 grains/time,three times daily.Patients in two groups were treated for 12 weeks.The clinical efficacies,the blood lipid indicators,hemorheology,and serum indicators in two groups were compared.Results After treatment,the total effective rate of the treatment group was 95.12%,while the total effective rate of the control group was 80.49%,with a significant difference between the groups(P<0.05).After treatment,HDL-C in two groups was higher than before treatment,but LDL-C,TG,and TC in two groups were lower than before treatment(P<0.05).HDL-C in the treatment group was higher than that in the control group,but LDL-C,TG,and TC in the treatment group were lower than that in the control group(P<0.05).After treatment,HCT,FIB,and PV in two groups were lower than those before treatment(P<0.05),and HCT,FIB,and PV in the treatment group were lower than those in the control group(P<0.05).After treatment,the serum levels of Hcy and VCAM-1 in two groups were significantly decreased,while the serum levels of ADPN in two groups were significantly increased(P<0.05).The serum levels of Hcy and VCAM-1 in the treatment group were lower than those in the control group,but the serum levels of ADPN were higher than those in the control group(P<0.05).Conclusion Xinmaitong Capsules combined with Rosuvastatin Calcium Tablets can improve the therapeutic effect of senile hyperlipidemia,significantly improve blood lipid level,improve hemorheology,and help reduce inflammation.
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