Objective To explore the clinical effect of Chuanshu Tablets combined with Salmeterol Xinafoate and Fluticasone Propionate Inhalation Aerosol in treatment of bronchial asthma.Methods Patients(120 cases)with bronchial asthma in Dingzhou People's Hospital from October 2021 to November 2023were randomly divided into control and treatment group,and each group had 60 cases.Patients in the control group were administered with Salmeterol Xinafoate and Fluticasone Propionate Inhalation Aerosol,1 press/time,twice daily.Patients in the treatment group were po administered with Chuanshu Tablets on the basis of the control group,2 tablets/time,three times daily.Patients in two groups were treated for 7 d.After treatment,the clinical evaluations were evaluated,the symptom relief time,the scores of ACT and AQLQ,and the levels of VEGF,VCAM-1,CRP,FeNO,FVC,FEV1 and FEV1/FVC in two groups before and after treatment were compared.Results After treatment,the clinical effective rate of the treatment group was 96.67%,which was significantly higher than that of the control group(83.33%,P<0.05).After treatment,the improvement time of cough,wheezing,chest pain and shortness of breath in the treatment group was significantly earlier than that in the control group(P<0.05).After treatment,ACT scores and AQLQ scores of the two groups were significantly higher than those before treatment(P<0.05),and ACT scores and AQLQ scores of the treatment group were significantly higher than those of the control group(P<0.05).After treatment,the levels of VEGF,VCAM-1,CRP and FeNO in two groups were significantly lower than those before treatment,while the levels of FVC,FEV1 and FEV1/FVC were significantly increased(P<0.05),and the above-mentioned indexes in the treatment group were significantly better than those in the control group(P<0.05).Conclusion Salmeterol fluticasone combined with Chuanshu Tablets can greatly improve the symptoms of patients with acute asthma,reduce the inflammatory response in the body,and significantly improve the quality of life.
Chuanshu TabletsSalmeterol Xinafoate and Fluticasone Propionate Inhalation Aerosolbronchial asthmaAQLQVEGFVCAM-1FeNO FVCFEV1
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