Objective To explore the efficacy of Shenqu Xiaoshi Oral Liquid combined with lacidophilin in treatment of functional dyspepsia in children.Methods A total of 104 children with functional dyspepsia treated in Daxing District People's Hospital of Beijing from April 2022 to June 2023 were selected and divided into control group(52 cases)and treatment group(52 cases)by random number table method.Children in control group chewed Lacidophilin Tablets,children<5 years old,0.4 g/time,children≥5 years old,0.8 g/time,3 times daily.Children in treatment group were po administered with Shenqu Xiaoshi Oral Liquid on the basis of control group,children<5 years old,5 mL/time,children≥5 years old,10 mL/time,3 times daily.Both groups were treated continuously for 2 weeks.The clinical efficacy and the improvement time of traditional Chinese medicine symptoms of two groups were observed,and the scores of functional dyspepsia life Quality Scale(FDDQL),serum motilin and neuropeptide Y levels were compared between two groups before and after treatment.Results After treatment,the total effective rate of treatment group was 96.15%,which was significantly higher than that of control group(84.62%,P<0.05).After treatment,the improvement time of food deficiency,abdominal fullness,and abdominal distension pain in treatment group was significantly shorter than that in control group(P<0.05).After treatment,FDDQL scores in both groups were higher than before treatment(P<0.05).The FDDQL score of treatment group was higher than that of control group(P<0.05).After treatment,the levels of motilin and neuropeptide Y in two groups were higher than before treatment(P<0.05).After treatment,motilin and neuropeptide Y levels in treatment group were higher than those in control group(P<0.05).Conclusions Shenqu Xiaoshi Oral Liquid combined with lacidophilin has good clinical efficacy in treatment of functional dyspepsia in children,and can improve the TCM symptoms,life quality and digestive function of children,increase their appetite,which has no obvious adverse reactions.
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