Objective To investigate the clinical efficacy of Tangniaole Capsules combined with Pioglitazone Hydrochloride Tablets in treatment of type 2 diabetes mellitus.Methods Patients(100 cases)with type 2 diabetes mellitus in Fengfeng General Hospital of North China Medical and Health Group from April 2020 to March 2023 were randomly divided into control and treatment groups,and each group had 50 cases.Patients in the control group were po administered with Pioglitazone Hydrochloride Tablets,2 tablets/time,once daily.Patients in the treatment group were po administered with Tangniaole Capsules on the basis of the control group,4 grains/time,three times daily.Patients in two groups were treated for 3 months.The clinical efficacies,main symptom resolution time,blood glucose indexes,and serum indexes in two groups were compared.Results After treatment,the total effective rate was 94.00%in the treatment group and 78.00%in the control group,with significant difference between groups(P<0.05).After treatment,the disappearance time of polydipsia,polyuria,and fatigue in the treatment group was significantly shorter than those in the control group(P<0.05).After treatment,FPG,PPG,and HbA1c in two groups were lower than those before treatment(P<0.05),and the blood glucose index in the treatment group was lower than those in the control group(P<0.05).After treatment,the serum levels of NLR,KIM-1,and NGAL in two groups were lower than those before treatment(P<0.05),and the levels of NLR,KIM-1 and NGAL in the treatment group were lower than those in the control group(P<0.05).Conclusion Tangniaole Capsules combined with Pioglitazone Hydrochloride Tablets can improve the curative effect of type 2 diabetes mellitus,further reduce blood sugar,promote the improvement of symptoms,and help reduce kidney damage.
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