Clinical study on Jingulian Capsules combined with Dexketoprofen Trometamol Tablets in treatment of rheumatoid arthritis of rheumatic obstruction type
Objective To explore the treatment of Jingulian Capsules combined with Dexketoprofen Trometamol Tablets in treatment of rheumatoid arthritis of rheumatic obstruction type.Methods Patients(100 cases)with rheumatoid arthritis of rheumatic obstruction type in Yuncheng Central Hospital affiliated to Shanxi Medical University from January 2022 to December 2022 were divided into control(50 cases)and treatment(50 cases)group according different drug use.Patients in the control group were po administered with Dexketoprofen Trometamol Tablets,12.5 mg/time,three times daily.Patients in the treatment group were po administered with Jingulian Capsule on the basis of the control group,5 grains/time,three times daily.Patients in two groups were treated for 4 weeks.After treatment,the clinical evaluations were evaluated,the TCM syndrome score,number of swollen joints and tender joints,the levels of ESR,TNF-α and IL-6 in two groups before and after treatment were compared.Results After treatment,the clinical effect of the treatment group was significantly better than that of the control group(98.00%vs 86.00%,P<0.05).After treatment,the scores of TCM syndrome,the number of swollen joints,the number of tenderness joints and the levels of ESR,TNF-α and IL-6 in two groups were significantly lower than those before treatment(P<0.05),and which in the treatment group were significantly lower than those in the control group(P<0.05).Conclusion Jingulian Capsules combined with Dexketoprofen Trometamol Tablets has high efficacy and safety in the treatment of rheumatoid arthritis,which can effectively reduce the inflammatory level of patients,reduce joint pain and improve TCM syndromes.