Clinical study on Fuke Duanhongyin Capsules combined with aminomethylbenzoic acid in treatment of abnormal uterine bleeding
Objective To explore the clinical efficacy of Fuke Duanhongyin Capsules combined with aminomethylbenzoic acid in treatment of abnormal uterine bleeding.Methods Patients(90 cases)with abnormal uterine bleeding in Zhangjiakou First Hospital from June 2021 to September 2023 were divided into control(45 cases)and treatment(45 cases)group according to random number table method.Patients in the control group were po administered with Aminomethylbenzoic Acid Tablets,0.5 g/time,three times daily.Patients in the treatment group were po administered with Fuke Duanhongyin Capsules on the basis of the control group,3 grains/time,three times daily.Patients in two groups were treated for 8 weeks.After treatment,the clinical evaluations were evaluated,the symptom relief time,and the levels of E2,FSH,P,LH,NO,TNF-α,IL-6 and VEGF in two groups before and after treatment were compared.Results After treatment,the clinical effective rate of the treatment group was 95.56%,which was significantly higher than that of the control group(80.00%,P<0.05).After treatment,the time of symptoms improvement in the treatment group was significantly earlier than that in the control group(P<0.05).After treatment,the levels of E2,FSH,P,LH,IL-6,NO,and TNF-α in two groups were significantly lower than those before treatment,but the serum levels of factor VEGF were significantly higher(P<0.05),these indicators levels in the treatment group were significantly better than those in the control group(P<0.05).Conclusion The synergistic treatment of Fuke Duanhongyin Capsules and aminomethylbenzoic acid can effectively improve clinical symptoms,significantly improve the level of sex hormones and reduce the inflammatory response.