Colorectal cancer has a high incidence rate and mortality.Drug treatment can prolong the survival period of patients,but there will be different degrees of drug resistance.β-Elemene is an active ingredient extracted from Curcumae Radix,which has a broad-spectrum anti-tumor activity.It can inhibit the growth and proliferation of tumor cells,induce tumor cell apoptosis,inhibit tumor cell invasion and metastasis,reverse tumor drug resistance,enhance the efficacy and toxicity of combined chemotherapy,increase sensitization with simultaneous radiotherapy,and improve immunization.This article provides an overview of research progress on mechanism of β-elemene in treatment of colorectal cancer,hoping to provide reference for β-elemene in clinical treatment of colorectal cancer.
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