Research progress on mechanism of emodin in prevention and treatment of atherosclerosis
Cardiovascular disease has become the most important disease threatening human health,and atherosclerosis is the main cause and pathological basis of cardiovascular disease.Emodin is an anthraquinone derivative obtained from Rhei Radix et Rhizoma and Polygoni Cuspidati Rhizoma,which has various pharmacological effects.Emodin can prevent and treat atherosclerosis by reducing inflammatory reaction,reducing oxidative stress reaction,regulating lipid metabolism,preventing vascular smooth muscle proliferation,protecting vascular endothelial function,stabilizing atherosclerotic plaque.This article reviews the research progress of mechanism of emodin in prevention and treatment of atherosclerosis,which provides a reference for the clinical application of emodin in prevention and treatment of atherosclerosis.
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