Clinical study on Qingke Pingchuan Granules in treatment of patients with mild and moderate COVID-19 infection
Objective To observe the clinical efficacy and safety of Qingke Pingchuan Granules in treatment of patients with mild and moderate COVID-19 infection.Methods Patients(93 cases)with mild and moderate COVID-19 infection in Changzhou Third People's Hospital from April 2023 to June 2023 were randomly divided into control(45 cases)and treatment(48 cases)group.Patients in the control group was treated with western medicine,and the basic treatment and antiviral treatment were carried out according to COVID-19's diagnosis and treatment plan(trial version 10).Patients in the treatment group were po administered with Qingke Pingchuan Granules on the basis of the control group,1 bag/time,three times daily.Patients in two groups were treated for 7 d.After treatment,the clinical evaluations were evaluated,the TCM syndrome scores,cough severity scores,the disappearance rate of major clinical symptoms,and inflammatory indicators in two groups before and after treatment were compared.Results After treatment,the clinical effective rate of the treatment group(97.92%)was significantly higher than that of the control group(86.67%,P<0.05).After treatment,the scores of TCM syndrome and cough degree in two groups were significantly decreased(P<0.05),and the therapeutic effect of the treatment group on the 7th day was significantly stronger than that of the control group(P<0.05).After treatment,compared with the control group,the treatment group could significantly promote the disappearance of cough symptoms(P<0.05).After treatment,the levels of inflammatory indexes IL-6 and CRP in two groups were significantly decreased(P<0.05),and which in the treatment group were significantly lower than those in the control group(P<0.05).Conclusion Qingke Pingchuan Granules in treatment of patients with mild and moderate COVID-19 infection can significantly improve the clinical effective rate,reduce the TCM syndrome score,improve the degree of cough,promote the relief and disappearance of cough symptoms,and reduce the level of inflammation,which has good safety and clinical popularization value.
NETL
NSTL
万方数据
