Clinical study on Baofukang Suppository combined with fleroxacin in treatment of chronic pelvic inflammatory disease
Objective To investigate the clinical effect of Baofukang Suppository combined with Fleroxacin Capsules in treatment of chronic pelvic inflammatory disease.Methods Patients(92 cases)with chronic pelvic inflammatory disease in Beijing Sixth Hospital from April 2022 to September 2023 were divided into control and treatment groups according to the random number method,and each group had 46 cases.Patients in the control group were po administered with Fleroxacin Capsules,2 grains/time,twice daily.Patients in the treatment group were given with Baofukang Suppository on the basis of the control group,after washing the external genitalia,pushing the Baofukang Suppository deep into the vagina,once daily.One course of treatment had 7 days,and patients in two groups were treated for 2 courses.After treatment,the clinical efficacies,the symptom relief time,ultrasound indicators,hemorheology,and serum indicators in two groups were compared.Results After treatment,the total effective rate of the treatment group was 93.48%,while the total effective rate of the control group was 78.26%,and the difference between the groups was statistically significant(P<0.05).After treatment,the relief time for lumbosacral pain,lower abdominal pain,excessive vaginal discharge,and fatigue in the treatment group was significantly shorter than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the maximum diameter of inflammatory masses and pelvic fluid accumulation in two groups were smaller than before treatment(P<0.05),and the maximum diameter of inflammatory masses and pelvic fluid accumulation in the treatment group were smaller than those in the control group(P<0.05).After treatment,the plasma viscosity,erythrocyte sedimentation rate,and fibrinogen in two groups were lower than before treatment(P<0.05),and the plasma viscosity,erythrocyte sedimentation rate,and fibrinogen in the treatment group were all lower than those in the control group(P<0.05).After treatment,the serum levels of IL-2 were higher than before treatment,but the serum levels of MCP-1 and TNF-α were lower than before treatment(P<0.05).After treatment,the serum levels of IL-2 in the treatment group was higher than that in the control group,but the serum levels of MCP-1 and TNF-α were lower than those in the control group(P<0.05).Conclusion Baofukang Suppository combined with Fleroxacin Capsules can further improve the therapeutic effect of chronic pelvic inflammatory disease,further reduce inflammatory mass,improve hemorheology level,and reduce inflammatory response.
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