Clinical study on Xihuang Pills combined with dexamethasone in treatment of plasma cell mastitis
Objective To investigate the clinical effect of Xihuang Pills combined with Dexamethasone Acetate Tablets in treatment of plasma cell mastitis.Methods Patients(114 cases)with plasma cell mastitis in Xingtai Central Hospital from October 2021 to September 2023 were divided into control and treatment groups according to the random number table method,and each group had 57 cases.Patients in the control group were po administered with Dexamethasone Acetate Tablets,4 tablets/time,twice daily.Patients in the treatment group were po administered with Xihuang Pills on the basis of the control group,3 g/time,twice daily.Patients in two groups were treated for 1 month.The clinical efficacies,the symptom disappearance time,degree of pain,ultrasound indicators,and serum indicators in two groups were compared.Results After treatment,the total effective rate of the treatment group was 92.98%,which was higher than 78.95%of the control group,and the difference was statistically significant(P<0.05).After treatment,the disappearance time of pain,redness,mass,and nipple discharge in the treatment group was shorter than that in the control group,and the difference was statistically significant(P<0.05).After treatment,VAS score of two groups was significantly decreased(P<0.05),and VAS score of the treatment group was lower than that of the control group(P<0.05).After treatment,SR and maximum diameter of breast mass were smaller than before treatment(P<0.05),and SR and maximum diameter of breast mass in the treatment group were smaller than those in the control group(P<0.05).After treatment,the serum levels of ICAM-1,TLR2,and IL-37 in two groups were lower than those before treatment(P<0.05),and the serum levels of ICAM-1,TLR2,and IL-37 in the treatment group were lower than those in the control group(P<0.05).Conclusion Xihuang Pills combined with Dexamethasone Acetate Tablets can improve the efficacy of plasma cell mastitis,further improve the clinical symptoms,reduce the pain degree of patients,and reduce the inflammatory response and tumor size.
Xihuang PillsDexamethasone Acetate Tabletsplasma cell mastitispain disappearance timeredness disappearance timemass disappearance timenipple discharge disappearance timeVAS scoreSRmaximum diameter of breast massICAM-1TLR2IL-37
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