Research progress on pharmacological effects of berberine in treatment of pulmonary infection
Pulmonary infections often occur in the form of pneumonia in clinical practice,and the core treatment is anti-infection.However,most pathogens have high resistance to traditional drugs.Berberine is an active ingredient extracted from Coptidis Rhizoma,which has various activities.Berberine can reduce pathogen resistance,prevent pathogen replication,alleviate pulmonary inflammatory response,regulate immune function,inhibit pulmonary fibrosis process,and protect vascular endothelial cells,so as to treat lung infection and reduce lung tissue damage.This article reviews the pharmacological research progress of berberine in treatment of pulmonary infections,providing a basis for the clinical treatment of pulmonary infections with berberine.
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