Research progress on pharmacological effects of tanshinone ⅡA in treatment of renal injury
Kidney disease can cause varying degrees of damage to renal tissue,leading to a decrease in renal function.Tanshinone ⅡA is a lipid soluble diterpenoid quinone isolated from Salviae Miltiorrhizae Radix et Rhizoma,which has various pharmacological effects.Tanshinone ⅡA can alleviate inflammation response,reduce oxidative stress reaction,delay renal tissue fibrosis,reduce cell apoptosis,enhance cell autophagy,improve hemorheology,and promote the efflux of harmful substances,thus it play a protective role in renal function.This article summarizes the pharmacological research progress of tanshinone ⅡA in treatment of kidney injury,providing reference for the clinical application of tanshinone ⅡA in kidney diseases.
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