Clinical observation of Jiangtang Tongmai Capsules combined with lilalutide in treatment of type 2 diabetes
Objective To investigate the therapeutic effect of Jiangtang Tongmai Capsules combined with lilalutide in treatment of type 2 diabetes.Methods Patients(98 cases)with type 2 diabetes in the Joint Logistics Support Force 987th Hospital from July 2022 to July 2023 were divided into control(49 cases)and treatment(49 cases)group according to the random number table method.Patients in control group were administered with Liraglutide Injection,the initial dose was 0.6 mg/d,and if the effect of blood glucose control was not ideal,the dose should be increased appropriately,and the maximum was not more than 1.8 mg/d.Patients in the treatment group were po administered with Jiangtang Tongmai Capsules on the basis of the control group,3 grains/time,three times daily.Patients in two groups were treated for 12 weeks.After treatment,the clinical evaluations were evaluated,the TCM symptom scores,and the levels of 2 h PBG,fasting blood glucose,HbA1c and HOMA-IR in two groups before and after treatment were compared.Results After treatment,the clinical effective rate of the treatment group was 95.92%,which was significantly higher than that of the control group(83.67%,P<0.05).After treatment,the scores of fatigue,thirst and drinking,shortness of breath and lazy talk,overeating and hunger were significantly decreased in two groups(P<0.05),and the scores in the treatment group were lower than those in the control group(P<0.05).After treatment,the levels of 2 h postprandial blood glucose(2 h PBG),fasting blood glucose,glycosylated hemoglobin(HbA1c)and insulin resistance index(HOMA-IR)were significantly decreased in two groups,and the blood glucose indexes in the treatment group were lower than those in the control group(P<0.05).Conclusion On the basis of Liraglutide Injection,Jiangtang Tongmai Capsules is effective in the treatment of type 2 diabetes,which can effectively improve the symptoms of traditional Chinese medicine,control the level of blood glucose and reduce insulin resistance.
Jiangtang Tongmai CapsulesLiraglutide Injectiontype 2 diabetes2 h PBGfasting blood glucoseHbA1cHOMA-IR
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