Clinical observation of Jianpi Shengxue Tablets combined with compound ferrous sulfate in treatment of iron deficiency anemia during pregnancy
Objective To explore the therapeutic effect of Jianpi Shengxue Tablets combined with compound ferrous sulfate in treatment of iron deficiency anemia during pregnancy.Methods Patients(106 cases)with iron deficiency anemia during pregnancy in Yan'an University Xianyang Hospital from October 2021 to October 2023 were divided into control group(53 cases)and treatment group(53 cases)according to random number table method.Patients in the control group were po administered with Compound Ferrous Sulfate Granules after meals,1 bag/time,once daily.Patients in the treatment group were po administered with Jianpi Shengxue Tablets on the basis of the control group,3 tablets/time,three times daily.Patients in two groups were treated for 4 weeks.After treatment,the clinical evaluations were evaluated,the improvement time for TCM symptoms,the levels of Hb,red blood cell count,hematocrit,hepcidin,ferritin and total iron binding capacity in two groups before and after treatment were compared.Results After treatment,the clinical effective rate of the treatment group was 94.34%,which was significantly higher than that of the control group(81.13%,P<0.05).Compared with the control group,the improvement time of fatigue,loss of appetite and sallow complexion in the treatment group was significantly shorter than that in the control group(P<0.05).Compared with before treatment,the levels of Hb,red blood cell count,hematocrit,ferritin were significantly increased,while the total iron binding capacity were significantly decreased in two groups(P<0.05),and compared with the control group,the improvement in the treatment group of there indexes was more obvious(P<0.05).Conclusion Jianpi Shengxue Tablets combined with compound ferrous sulfate in treatment of iron deficiency anemia during pregnancy can obtain better clinical effect,and effectively improve the TCM symptoms,erythrocyte related indexes and iron metabolism of patients.
Jianpi Shengxue TabletsCompound Ferrous Sulfate Granulesiron deficiency anemia during pregnancyhematocrithepcidinferritintotal iron binding capacity
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